Search on: COMPLEMENT INACTIVATOR PROTEINS 
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Descriptor English:   Complement Inactivator Proteins 
Descriptor Spanish:   Proteínas Inactivadoras de Complemento 
Descriptor Portuguese:   Proteínas Inativadoras do Complemento 
Tree Number:   D12.776.124.486.274.920
Definition English:   Serum proteins that negatively regulate the cascade process of COMPLEMENT ACTIVATION. Uncontrolled complement activation and resulting cell lysis is potentially dangerous for the host. The complement system is tightly regulated by inactivators that accelerate the decay of intermediates and certain cell surface receptors. 
Indexing Annotation English:   do not confuse with COMPLEMENT INACTIVATING AGENTS
Pharmacological Action:   Complement Inactivating Agents
 
History Note English:   2006 (1978) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22145 
Unique Identifier:   D003169 

Occurrence in VHL:
 

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